An easy to use tool to address questions pertaining to ‘size’ and 'sample quality'
Facilitates the optimization of sample conditions (buffers and/or constructs); assesses oligomerisation/aggregation state; and gives an idea of sample heterogeneity (be it from variable oligomeric state or impurities).
Sensitivity down to 25µM depending on particle molar mass - intensity is directly proportional to the product of the molar mass and the molecular concentration... (25µM for 15kDa; 5µM for 150kDa).
Using standard microwell plates: 96 (80µL sample), 384 (10µL sample), or 1536 (4µL sample)
Temperature from 4°C to 80°C (including ramping experiments)
Determines the hydrodynamic radius from 0.5nm to 1000nm